American Board of Dental Examiners (ADEX) Dental Hygiene Licensing Examination

Anticholinesterase medications are commonly used to manage the symptoms of myasthenia gravis because this condition is characterized by a defect in the transmission of nerve impulses to muscles, leading to muscle weakness. Myasthenia gravis results from antibodies blocking or destroying the nicotinic acetylcholine receptors at the neuromuscular junction, which interferes with the communication between nerves and muscles. Anticholinesterase medications, such as pyridostigmine, work by inhibiting the enzyme acetylcholinesterase, which breaks down acetylcholine in the synaptic cleft. By preventing the breakdown of acetylcholine, these medications increase its availability at the neuromuscular junction, thereby enhancing muscle contraction and temporarily alleviating the weakness associated with myasthenia gravis. The other treatments listed are not appropriate for managing myasthenia gravis symptoms. Insulin therapy is directed towards managing diabetes; iron supplements are used for anemia; and chemotherapy is primarily for cancer treatment. Therefore, anticholinesterase medications are the most relevant and effective choice for those suffering from myasthenia gravis.